Pathogenesis of Shigellosis

· Current Topics in Microbiology and Immunology Книга 180 · Springer Science & Business Media
Π•-ΠΊΠ½ΠΈΠ³Π°
143
Π‘Ρ‚Ρ€Π°Π½ΠΈΡ†ΠΈ
ΠžΡ†Π΅Π½ΠΈΡ‚Π΅ ΠΈ Ρ€Π΅Ρ†Π΅Π½Π·ΠΈΠΈΡ‚Π΅ Π½Π΅ сС ΠΏΠΎΡ‚Π²Ρ€Π΄Π΅Π½ΠΈ Β Π”ΠΎΠ·Π½Π°Ρ˜Ρ‚Π΅ повСќС

Π—Π° Π΅-ΠΊΠ½ΠΈΠ³Π°Π²Π°

Shigellosis is present all over the world. Anyone traveling in developing countries knows that the control of this invasive disease of the intestine is a priority task for physicians and public health authorities. Victims are essentially young children, and complications such as the hemolytic uremic syndrome make shigellosis a systemic disease rather than simply an infection of the colonic mucosa. However, "Westerners" should not consider shigeJlosis as an unlikely threat of the tropics. The disease arises in industrialized countries as soon as breaches in sanitation appear. A few months ago, at least 500 people developed shigellosis in northern France in an outbreak of Shigella sonnei infection due to accidental contamination of an urban water delivery system. The pathogenesis of shigellosis is an extraordinary topic of research because study of the invasion of the colonic mucosa addresses fundamental questions on. the molecular and cellular mechanisms by which a bacterial pathogen can pene trate non phagocytic cells, survive, multiply, spread in the intra cellular compartment, and eventually kill host cells. Further development of the infection within subepithelial tissues as well as the mechanisms that contribute to the eradication of this process have barely been studied.

ΠžΡ†Π΅Π½Π΅Ρ‚Π΅ ја Π΅-ΠΊΠ½ΠΈΠ³Π°Π²Π°

ΠšΠ°ΠΆΠ΅Ρ‚Π΅ Π½ΠΈ ΡˆΡ‚ΠΎ мислитС.

Π˜Π½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ Π·Π° Ρ‡ΠΈΡ‚Π°ΡšΠ΅

ΠŸΠ°ΠΌΠ΅Ρ‚Π½ΠΈ Ρ‚Π΅Π»Π΅Ρ„ΠΎΠ½ΠΈ ΠΈ Ρ‚Π°Π±Π»Π΅Ρ‚ΠΈ
Π˜Π½ΡΡ‚Π°Π»ΠΈΡ€Π°Ρ˜Ρ‚Π΅ ја Π°ΠΏΠ»ΠΈΠΊΠ°Ρ†ΠΈΡ˜Π°Ρ‚Π° Google Play Books Π·Π° Android ΠΈ iPad/iPhone. Автоматски сС синхронизира со смСтката ΠΈ Π²ΠΈ ΠΎΠ²ΠΎΠ·ΠΌΠΎΠΆΡƒΠ²Π° Π΄Π° Ρ‡ΠΈΡ‚Π°Ρ‚Π΅ онлајн ΠΈΠ»ΠΈ ΠΎΡ„Π»Π°Ρ˜Π½ ΠΊΠ°Π΄Π΅ ΠΈ Π΄Π° стС.
Π›Π°ΠΏΡ‚ΠΎΠΏΠΈ ΠΈ ΠΊΠΎΠΌΠΏΡ˜ΡƒΡ‚Π΅Ρ€ΠΈ
МоТС Π΄Π° ΡΠ»ΡƒΡˆΠ°Ρ‚Π΅ Π°ΡƒΠ΄ΠΈΠΎΠΊΠ½ΠΈΠ³ΠΈ ΠΊΡƒΠΏΠ΅Π½ΠΈ ΠΎΠ΄ Google Play со ΠΊΠΎΡ€ΠΈΡΡ‚Π΅ΡšΠ΅ Π½Π° Π²Π΅Π±-прСлистувачот Π½Π° ΠΊΠΎΠΌΠΏΡ˜ΡƒΡ‚Π΅Ρ€ΠΎΡ‚.
Π•-Ρ‡ΠΈΡ‚Π°Ρ‡ΠΈ ΠΈ Π΄Ρ€ΡƒΠ³ΠΈ ΡƒΡ€Π΅Π΄ΠΈ
Π—Π° Π΄Π° Ρ‡ΠΈΡ‚Π°Ρ‚Π΅ Π½Π° ΡƒΡ€Π΅Π΄ΠΈ со Π΅-мастило, ΠΊΠ°ΠΊΠΎ ΡˆΡ‚ΠΎ сС Π΅-Ρ‡ΠΈΡ‚Π°Ρ‡ΠΈΡ‚Π΅ Kobo, ќС Ρ‚Ρ€Π΅Π±Π° Π΄Π° ΠΏΡ€Π΅Π·Π΅ΠΌΠ΅Ρ‚Π΅ Π΄Π°Ρ‚ΠΎΡ‚Π΅ΠΊΠ° ΠΈ Π΄Π° ја ΠΏΡ€Π΅Ρ„Ρ€Π»ΠΈΡ‚Π΅ Π½Π° ΡƒΡ€Π΅Π΄ΠΎΡ‚. Π‘Π»Π΅Π΄Π΅Ρ‚Π΅ Π³ΠΈ Π΄Π΅Ρ‚Π°Π»Π½ΠΈΡ‚Π΅ упатства Π²ΠΎ Π¦Π΅Π½Ρ‚Π°Ρ€ΠΎΡ‚ Π·Π° помош Π·Π° ΠΏΡ€Π΅Ρ„Ρ€Π»Π°ΡšΠ΅ Π½Π° Π΄Π°Ρ‚ΠΎΡ‚Π΅ΠΊΠΈΡ‚Π΅ Π½Π° ΠΏΠΎΠ΄Π΄Ρ€ΠΆΠ°Π½ΠΈ Π΅-Ρ‡ΠΈΡ‚Π°Ρ‡ΠΈ.