Morphological, molecular and biochemical characterization of selected banana varieties in Kerala and evaluation of their anticancer activities: an overview

Prem Jose Vazhacharickal · Anu Augustine · Sajeshkumar N. K · Jiby John Mathew · P. E Sreejith · M. Sabu

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Banana is one of the most important food crops all over the world. There are around 365 varieties of bananas available throughout the world. Banana is a traditional medicine for diabetes, cancer, diarrhoea and also highly nutritional food crop. In this study, commonly used varieties of banana are taken for characterization by morphology and genotype which is based on International Plant Genetic Resources Institute and RAPD analysis. Five varieties were morphologically similar in parameters such as leaf habit, pseudo stem appearance and peel color. RAPD analysis proved that these varieties of banana are closely related which coincides with the morphological characterization. Also, this study is aimed at examining the anticancer activity of Musa acuminata variety of banana which is commonly consumed in southern part of India. Anticancer examination of the sample was performed for the hexane extract using DLA and MG-63 cell lines which showed a high degree of anticancer activity which was proved by the cytotoxic effect on the tumor cell lines. Phytochemicals present in the plant concentrate provoked cell apoptosis and smoother cell expansion to quickly partitioning malignancy cell lines. Among the five varieties analysed, Musa accuminata Colla variety shows increased level of anticancer activity in both cell lines. So it is anticipated that this variety can be used as medicine orally for cancer treatment.