These proceedings feature 20 original publications from distinguished authors in the cross-section of computational sciences, such as machine learning algorithms and probabilistic models, complex networks and fitness landscape analysis, set oriented numerics and cell mapping, evolutionary multiobjective optimization, diversity-oriented search, and the foundations of genetic programming algorithms. By presenting cutting edge results with a strong focus on foundations and integration aspects this work presents a stepping stone towards efficient, reliable, and well-analyzed methods for complex systems management and analysis.