Extracellular Vesicles in Health and Disease
Paul Harrison · Chris Gardiner · Ian L. Sargent
Mei 2014 · CRC Press
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Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role
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Paul Harrison is the Healing Foundation senior lecturer within the School of Immunity and Infection at the University of Birmingham, UK. He is a former president of the British Society of Haemostasis and Thrombosis. He has published over 120 papers and book chapters/reviews in his field. In 2010, Paul was featured as one of the top 100 healthcare scientists in the United Kingdom by the Department of Health. He is also an associate editor of the Journal of Extracellular Vesicles and a member of the editorial board of Platelets and the Journal of Thrombosis and Haemostasis.
Chris Gardiner
is scientific secretary of the British Society for Haemostasis and Thrombosis and a board member of both the International Society of Extracellular Vesicles and International Society of Laboratory Hematology. He serves on the editorial board of the Journal of Extracellular Vesicles and the International Journal of Thrombosis and Haemostasis. He has vast experience on the measurement and characterization of extracellular vesicles in the early detection of human disease.Ian L. Sargent
is professor of reproductive science in the Nuffield Department of Obstetrics and Gynaecology, University of Oxford, UK. He has worked in the field of reproductive immunology and trophoblast biology for more than 30 years and has over 150 publications on a wide range of topics including pre-eclampsia, feto-maternal cell traffic, HLA-G, and early human embryo development and implantation. A major focus of his work has been the isolation and characterization of placental extracellular vesicles and their role in the pathogenesis of pre-eclampsia.Gradeer hierdie e-boek
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