Meanwhile her dramatic instinct had begun to work upon the material thus gathered. It was impossible for her, with her strong religious nature and her active interest in structural Christianity to avoid subjecting the great church so constantly in evidence to those tests of personal religion which had been familiar to her from childhood. Her stay in Florence brought vividly before her the figure of Savonarola, and her imagination, in seeking to recover the life of his day, instinctively invested it with the spiritual struggles so well known to her and her circle. There was no conscious protestantizing of the life, as one may say, but the story which she told naturally reflected the color of her own religious training. Agnes of Sorrento was begun in this Italian winter, and had its immediate origin, as she herself explains in the following note, in a friendly contest of story telling. It was not completed until some time after the return to America, finding its first publication in The Atlantic Monthly in America and The Cornhill Magazine in England. In The Atlantic it was begun in May, 1861, and finished in April, 1862.
In the party with Mrs. Stowe were Mr. and Mrs. Howard of Brooklyn, and their children. When the tale made its final appearance in book form, it was accompanied by the following passages from a letter to the publishers by Mrs. Stowe. The "Annie" referred to was Miss Annie Howard.